Home | Login | Subscribe Today!Nov. 20, 2009

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Pharmacist’s Letter addresses the drug therapy issues facing pharmacists. For example:

  • Does sitagliptin (Januvia) and sitagliptin/metformin (Janumet) increase the risk for pancreatitis?
  • What is the possible mechanism for acute pancreatitis caused by sitagliptin or Byetta (exenatide)?
  • Is this higher risk of acute pancreatitis a class effect?
  • How does diabetes itself effect the risk of pancreatitis?
  • What should diabetes patients do if they develop unexplained abdominal pain?
  • Should similar precautions be used for the other gliptin, saxagliptin (Onglyza)?
For answers see our article: new warnings about reports of acute pancreatitis with sitagliptin (Januvia, Janumet)

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Additional information is available in our Detail-Document:

Januvia (Sitagliptin) and Pancreatitis

   

FDA is revising the prescribing information for Januvia (sitagliptin) and Janumet (sitagliptin/metformin) to include information on reported cases of acute pancreatitis in patients using these products.

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